Study on development and tissue permeation of different formulations of Fasudil.

A Unnisa,N E Khalifa, W M A Khojali, M E Osman,A H Alshammari,H S Alshammari, M G Alanazi, N Bandar, S B Jandrajupalli, B A Elamine,O A Mohamed, R Gangireddy

European review for medical and pharmacological sciences（2023）

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摘要

The study concluded that the typical gel formulation (liposomal Fasudil dispersed in hydroxypropyl methylcellulose solution, which is added to blank poloxamer 407) had been shown to have significantly anti-anginal properties, including easy administration, its application on the infarct area percentage and subsequently its pharmacological effect on the cardiac tissue.

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关键词

fasudil,tissue permeation,different formulations

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