The impact of surgical resection margins on outcomes for adults with head and neck osteosarcomas: A Canadian sarcoma research and Clinical Collaboration (CanSaRCC) study

•Osteosarcomas of the head and neck are rare and recurrence are mainly local.•Surgery is the principal therapeutic modality for resectable head and neck osteosarcomas, however, chemotherapy and/or radiotherapy are being considered for patients with high-grade lesions, pathological adverse features or close margins resection.•Surgical resection with negative resection margins may improve survival, and a 3 mm resection margin threshold may optimize survival.