Mitochondrial apoptosis-related gene polymorphisms are associated with responses to anthracycline-based chemotherapy in acute myeloid leukaemia.

Guangqiang Meng,Mingying Li,Yuan Xia,Yuyan Wu, Yuechan Ma,Min Ji,Jingru Zhang,Jingjing Ye,Tao Sun,Chunyan Ji

Frontiers in oncology（2023）

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摘要

Our results about the association of SNPs in mitochondrial apoptosis-related genes with the response to anthracycline-based chemotherapy in AML provide an important reference for predicting the treatment outcomes in patients with this disease.

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关键词

acute myeloid leukemia,mitochondrial apoptosis,single nucleotide polymorphisms,anthracyclines,CRISPR/Cas9

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