Reverse genetics in virology: A double edged sword

Biosafety and Health（2022）

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摘要

•Molecular biology and synthetic biology have promoted the development of reverse genetics.•Reverse genetics has made great contributions to virology and development of anti-viral strategy.•Reverse genetics in virology has aroused global concerns of biosafety and biosecurity.•Safe and efficient use of reverse genetics needs public awareness, education of stakeholder, regulation and governance.

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关键词

Reverse genetics,Virology,Dual use research of concern,Biosafety,Biosecurity,Regulation

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