Prospective collection of blood plasma samples to identify potential biomarkers for the prehospital stroke diagnosis (ProGrEss-Bio): study protocol for a multicenter prospective observational study.

Frederik Geisler,Lisa Haacke,Maren Lorenz,Eugen Schwabauer,Matthias Wendt, Lydia Bernhardt, Eman Dashti,Erik Freitag,Alexander Kunz, Christina Hofmann-Shen, Martina Zuber,Carolin Waldschmidt,Farid I Kandil,Kai Kappert,Chantip Dang-Heine,Irina Lorenz-Meyer,Heinrich J Audebert,Joachim E Weber

Frontiers in neurology（2023）

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摘要

This study will evaluate whether a single blood biomarker or a combination of biomarkers can distinguish patients with AIS and ICH from patients with stroke and SM in the early phase after symptom onset in the prehospital setting. In addition, the kinetics of blood biomarkers in AIS and ICH patients will be investigated. Our goal is to evaluate new ways to reliably diagnose stroke in the prehospital setting and thus accelerate the application of evidence-based therapies to stroke patients.

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关键词

cerebrovascular disease, stroke, intracerebral hemorrhage, prehospital emergency medicine, emergency medicine, mobile stroke units, biomarkers, stroke mimics

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