Hodgkin Lymphoma and Female Fertility: A Multicenter Study of Fertility in Women Treated with Doxorubicin, Bleomycin, Vinblastine and Dacarbazine
Blood(2017)
摘要
Background: Hodgkin Lymphoma (HL) is a curable lymphoid malignancy affecting a young population of child-bearing age. Many young women are cured and face long-term complications. Among them, infertility holds an important place and the preservation of fertility has become a growing issue. First-line chemotherapy with ABVD (Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine) appears to have low gonadotoxicity, but this toxicity has been rarely studied.
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