Pericardial irradiation dose may be strongly associated with grade 4 lymphopenia and affect prognosis in patients with locally advanced esophageal cancer receiving definitive concurrent chemoradiotherapy.
Thoracic cancer(2023)
摘要
Higher doses of pericardial radiation might affect LA-EC patients' prognosis by inducing G4 lymphopenia during CCRT. Further prospective studies are warranted to confirm these findings, especially in the era of immune-checkpoint inhibitor treatment.
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关键词
concurrent chemoradiotherapy, immune-checkpoint inhibitor, locally advanced esophageal cancer, lymphopenia, pericardial irradiation
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