Human precision-cut cystic duct and gallbladder slices: a novel method for studying cholangiopathies.

Jeske Fridrichs, Bart Hamel, Wendy Kelder, Ewoud van den Hoed,Marius C van den Heuvel,Jan B F Hulscher,Peter Olinga

Frontiers in pediatrics(2023)

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摘要
This study is the first to report on the use of the PCTS model for human gallbladder and cystic duct tissue. PCCDS and PCGS remain viable for an incubation period of at least 24 h, which makes them suitable for research purposes in the field of cholangiopathies, including biliary atresia.
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关键词
precision-cut tissue slices (PCTS), cholangiopathies, ex vivo culture technique, cystic duct, gallbladder
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