SETD1A-mediated H3K4me3 methylation upregulates lncRNA HOXC-AS3 and the binding of HOXC-AS3 to EP300 and increases EP300 stability to suppress the ferroptosis of NSCLC cells.
Thoracic cancer（2023）
摘要
SETD1A-mediated H3K4me2 methylation promoted HOXC-AS3 expression, binding of HOXC-AS3 to EP300, and EP300 stability, thereby suppressing NSCLC cell ferroptosis.
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关键词
ferroptosis,H3K4me3,lncRNA HOXC‐AS3,non‐small cell lung cancer,SETD1A
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