One-Pot Multi-Component Synthesis of Polysubstituted Pyridines Using DBU-SiO₂ as a Robust Recyclable Catalyst

Chiranjeevi Yakkanti,Vaikunta L. Rao,Nagaraju Kerru,Simhachalam Gorle, Shankar Madhavaram,Raghunadh Akula,Sandeep V. H. S. Bhaskaruni

POLYCYCLIC AROMATIC COMPOUNDS（2024）

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摘要

We report an efficient novel route for the synthesis of polysubstituted pyridine derivatives with DBU-SiO2 catalyzed one-pot four-component reaction. This protocol offers a mild condition that which affords a series of new polysubstituted pyridine derivatives with good yields. A plausible mechanism for this process is proposed.

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Multi-component reaction,polysubstituted pyridine,DBU-SiO2,heterogeneous catalyst

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One-Pot Multi-Component Synthesis of Polysubstituted Pyridines Using DBU-SiO2 as a Robust Recyclable Catalyst

One-Pot Multi-Component Synthesis of Polysubstituted Pyridines Using DBU-SiO₂ as a Robust Recyclable Catalyst