Bacterial and Fungal Co-Infection: an Association of Criminals to Look For

Introduction - Mucorales are fungi that cause opportunistic infections. Its incidence increases. Case report. - We report case of a 68-year-old woman with myelodysplastic syndrome responsible for prolonged neutropenia, hospitalized for pneumonia and sinusitis caused byPseudomonas aeruginosa. But, despite antibiotic therapy, the patient's health deterioratedwith discovery of systemic emboli on CT-scan and died. Sinus biopsies performed before herdeath diagnosed invasive fungal infection (Mucorales). Conclusion. - Mucorales co-infections are rare but have already been described. Any invasivefungal infection should be searched on the event of any clinical suspicion: ground (neutropenia), lack of response to well-conducted antibiotic therapy, rapidly unfavorable outcome. Thepresence of other microbiological documentation do not must stop the search of invasive fungalinfection, because it could have short-term life-threatening impact. (c) 2022 SPLF. Published by Elsevier Masson SAS. All rights reserved.