Evaluation of therapeutic potential of cannabidiolbased products in animal models of epileptic seizures, neuropathic pain and chronic inflammation

FARMACIA(2022)

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摘要
Cannabidiol (CBD) is one of the main cannabinoids (CBi) found in Cannabis species. The purpose of this study is to present the evaluation of the anticonvulsant effect in an animal model of epileptic seizures induced by the administration of electric shocks to mice for acute treatment with 3 vegetable oils with CBD. We also evaluated the antihyperalgic effect in a neuropathy model, and anti-inflammatory and analgesic potential of the CBD-containing emulsion after local administration. Significant anticonvulsant and antihyperlagic effects were observed for CBD-containing oils.
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关键词
cannabidiolbased products,epileptic seizures,therapeutic potential
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