Generalized methods for predicting biological response to mixed radiation types and calculating equieffective doses (EQDX).

The mZRM is a computationally efficient model that can be used to predict biological response to mixed radiations that have low- and high-LET characteristics. Importantly, interaction terms are retained in the calculation of EQDX for mixed radiation exposures within the mZRM framework. The mZRM has application in a wide range of radiation therapies, including radiopharmaceutical therapy. This article is protected by copyright. All rights reserved.