[A comparison of DNA methylation profiles of blood mononuclear cells in patients with multiple sclerosis in remission and relapse].

I S Kiselev, O G Kulakova,O A Baturina,M R Kabilov, A N Boyko,O O Favorova

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova（2023）

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摘要

For the first time it was shown that during relapse and remission of RRMS there are differences in the DNA methylation profile that allow discrimination between these clinical stages. These data indicate the involvement of the epigenetic mechanism of DNA methylation in the activation of the pathological process in RRMS.

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multiple sclerosis,dna methylation profiles,blood mononuclear cells

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