A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

Vineet D Menachery,Boyd L Yount Jr,Kari Debbink,Sudhakar Agnihothram,Lisa E Gralinski,Jessica A Plante,Rachel L Graham,Trevor Scobey,Xing-Yi Ge,Eric F Donaldson,Scott H Randell,Antonio Lanzavecchia,Wayne A Marasco,Zhengli-Li Shi,Ralph S Baric

Nature Medicine（2015）

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摘要

Ralph Baric, Vineet Menachery and colleagues characterize a SARS-like coronavirus circulating in Chinese horseshoe bats to determine its potential to infect primary human airway epithelial cells, cause disease in mice and respond to available therapeutics.

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