High-performance non-enzymatic glucose sensor based on Co3O4/rGO nanohybrid

There has been substantial interest in designing and fabricating electrochemical non-enzyme sensors for glucose detection with a focus on the nanocomposites used between metal oxide and the two-dimensional material. In this work, Co3O4/reduced graphene oxide (rGO) nanocomposite was obtained and used as a modified electrochemical electrode for the detection of trace glucose. According to the results, the electrocatalytic performances of Co3O4 nanoparticles for the oxidation of glucose were substantially enhanced with the addition of a small amount of rGO. Specifically, the Co3O4/rGO modified electrode exhibited a sensitivity of 82 μA·mmol−1·cm−2, a detection limit of 50 μmol·L−1 (signal noise ratio (S/N) = 3), and a fast response time of about 1 s under optimal conditions. The enhanced performances of the Co3O4/rGO modified electrode are attributable to the high absorption oxygen (OAds) and synergistic effect between Co3O4 and rGO. The results indicate that Co3O4/rGO nanocomposite is a promising candidate for being used as the active material in real-world electrochemical biosensors.