Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma: Association with Metabolic Tumor Burden Determined with FDG-PET/CT.

Antti Silvoniemi,Jukka Laine,Katri Aro,Linda Nissi,Leif Bäck,Jukka Schildt,Jussi Hirvonen,Jaana Hagström,Heikki Irjala,Leena-Maija Aaltonen,Marko Seppänen,Heikki Minn

Cancers（2023）

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摘要

A high metabolic tumor burden based on FDG imaging is associated with a positive liquid biopsy and high maximum VAF. Our findings suggest a complementary role of metabolic and genomic signatures in the pre-treatment evaluation of HNSCC.

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关键词

metabolic tumor burden,tumor dna,neck squamous cell carcinoma,squamous cell carcinoma,fdg-pet

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