Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma.

Keren Li,Yi Niu,Kai Li,Chengrui Zhong,Zhiyu Qiu,Yichuan Yuan,Yunxing Shi,Zhu Lin,Zhenkun Huang,Dinglan Zuo,Yunfei Yuan,Binkui Li

Journal of clinical and translational hepatology（2023）

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摘要

High expression of PLOD2 was regulated by IRF5, which was correlated with the poor survival of HCC patients. PLOD2 enhanced HCC metastasis via BIRC3, suggesting that PLOD2 might be a valuable prognostic biomarker for HCC treatment.

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关键词

PLOD2, Hepatocellular carcinoma, Metastasis, Invasion, Prolifera-tion

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