Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma.

Journal of clinical and translational hepatology(2023)

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摘要
High expression of PLOD2 was regulated by IRF5, which was correlated with the poor survival of HCC patients. PLOD2 enhanced HCC metastasis via BIRC3, suggesting that PLOD2 might be a valuable prognostic biomarker for HCC treatment.
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关键词
PLOD2, Hepatocellular carcinoma, Metastasis, Invasion, Prolifera-tion
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