Challenges in posterior uveitis-tips and tricks for the retina specialist.

Manuel Paez-Escamilla,Sonny Caplash,Gagan Kalra, Jamie Odden, Danielle Price, Oscar C Marroquin, Stephen Koscumb, Patrick Commiskey, Chad Indermill, Jerome Finkelstein, Anna G Gushchin, Andreea Coca,Thomas R Friberg,Andrew W Eller, Denise S Gallagher,Jean C Harwick,Evan L Waxman,Jay Chhablani,Gabrielle Bonhomme, Colin Prensky, Alexander J Anetakis, Joseph N Martel, Erika Massicotte, Raphaelle Ores,Jean-Francois Girmens, Thomas M Pearce,Jose-Alain Sahel,Kunal Dansingani,Mark Westcott,Marie-Helene Errera

Journal of ophthalmic inflammation and infection(2023)

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This review of unique posterior uveitis cases highlights the overlapping features of posterior uveitis (paradoxical inflammatory effects of anti -TNF α and uveitis; Purtscher-like retinopathy as a presentation of systemic lupus erythematosus, …) and the nature of retinal conditions (ischemic ocular syndrome, or central retinal vein occlusion, amyloidosis, inherited conditions like retinitis pigmentosa, autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV), etc.…) that may mimic them is represented. Careful review of past uveitis history, current medications and recent vaccinations, detailed examination of signs of past or present inflammation, eventually genetic testing and/ or multimodal retinal imaging (like fluorescein angiography, EDI-OCT, OCT-angiography for lupus Purtscher-like retinopathy evaluation, or ICG for central serous retinopathy, or retinal amyloid angiopathy) may aid in correct diagnosis.
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