Impact of hs-CRP concentration on brain structure alterations and cognitive trajectory in Alzheimer's disease.

Ye Zhang,Yasuko Tatewaki,Taizen Nakase,Yingxu Liu,Naoki Tomita,Benjamin Thyreau,Haixia Zheng,Michiho Muranaka,Yumi Takano,Tatsuo Nagasaka,Yasuyuki Taki

Frontiers in aging neuroscience（2023）

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摘要

Our study suggests that increased hs-CRP level may exert protective effect on brain structure alterations and future cognitive changes among patients already with cognitive impairment.

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关键词

gray matter volume, systemic inflammation, C-reactive protein, FreeSurfer, subjective cognitive decline, Alzheimer's disease

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