Reduced DEFA5 Expression and STAT3 Activation Underlie the Submucosal Invasion of Early Gastric Cancers.

Sayaka Nagao,Yu Takahashi,Tamami Denda,Yukihisa Tanaka,Yuko Miura,Hiroya Mizutani,Daisuke Ohki,Yoshiki Sakaguchi,Seiichi Yakabi,Yosuke Tsuji,Keiko Niimi,Naomi Kakushima,Nobutake Yamamichi,Yasunori Ota,Kazuhiko Koike,Mitsuhiro Fujishiro

Digestion（2023）

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摘要

The results of this study strongly suggest that the downregulation of DEFA5 and the activation of STAT3 play a significant role in the submucosal invasion of EGC.

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关键词

Gastric cancer, Submucosal invasion, DEFA5, STAT3

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