The role and mechanism of myeloperoxidase in dermatomyositis.

Lijuan Zhao,Chuyu Shen,Shasha Xie,Junyu Zhou,Huali Zhang,Honglin Zhu,Yisha Li,Siming Gao

International immunopharmacology（2023）

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摘要

Our study disclosed, for the first time, that MPO plays an important role in promoting inflammatory infiltration and inducing muscle damage in DM patients. MPO may be a potential biomarker for DM muscle involvement and MPO targeted drugs may be promising in DM treatment.

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关键词

Dermatomyositis,Inflammatory cell migration,Muscle atrophy,Myeloperoxidase,Vascular permeability

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