Bone marrow mesenchymal stem cell derived exosomal miR-455-5p protects against spinal cord ischemia reperfusion injury

Bing Liu, Wenjun Zheng,Li Dai,Shengjie Fu,Enyi Shi

Tissue and Cell（2022）

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摘要

•Exosomal miR-455-5p alleviates spinal cord ischemia reperfusion (SCIR) injury.•Exosomal miR-455-5p inhibits apoptosis of neurons in the injured spinal cord.•Exosomal miR-455-5p activates autophagy pf neurons in the injured spinal cord.

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SCIR,BMSCs,PBS,TEM,NTA,BBB,CNS

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