The promoting effect of modified Dioscorea pills on vascular remodeling in chronic cerebral hypoperfusion via the Ang/Tie signaling pathway.

Guiying Kuang, Zhigang Shu, Chunli Zhu,Hongbing Li, Cheng Zhang

Translational neuroscience（2023）

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摘要

CCH induces microvascular neogenesis in the hippocampus, and MDP promotes angiogenesis and microcirculation remodeling in CCH rats via the Ang/Tie signaling pathway, which may be an important mechanism for its restorative effects on hippocampal perfusion and improvement of cognitive function in CCH rats.

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关键词

chronic cerebral hypoperfusion,dioscorea pills,vascular remodeling

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