Integrating Network Pharmacology and Experimental Validation to Explore the Effects and Mechanisms of Qinghao Biejia Decoction and Its Active Compound Artemisinin B Against Non-Small-Cell Lung Cancer.

Yonghua Ye,Yuping Yang,Li Yan,Li Zhou,Shihui Yu,Quan Du,Xiaoqiao Dong,Qiang Yuan,Letian Shan,Le Guo

Drug design, development and therapy（2023）

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摘要

This study revealed the anti-NSCLC efficacy of QBD. ART B, the effective component of QBD, plays an anti-NSCLC role by down-regulating the PI3K-Akt signaling pathway. It suggests that QBD and ART B are promising drug candidates for NSCLC treatment.

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关键词

qinghao biejia decoction,lung cancer,integrating network pharmacology,non-small-cell

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