High Transcriptional Activity and Clinical Correlations in Eosinophils of Patients with Late-Onset Asthma.

This study describes differences in the transcriptional active patterns of eosinophils and their correlation to atopy and obesity by age of onset. High transcriptional activity in activated eosinophils and a negative correlation to lung function indicate the importance of eosinophils in the pathogenesis of LOA.