Vitamin B-12 and a metal-organic framework enable the photocatalytic generation of alkyl radicals

A versatile Co-catalyst-vitamin B-12 (cobalamin)-can be photochemically reduced to its catalytically active Co(i) form under visible light irradiation, in the presence of MIL-125-NH2(Ti) as a photocatalyst and utilized for the generation of alkyl radicals. The prior reduction of cobalamin to the Co(ii) form is not required in this method.