Pausing pluripotency via RNA methylation

Nature Cell Biology(2023)

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摘要
Embryonic diapause in development and paused pluripotency in embryonic stem cells result in a state of hypotranscription through mechanisms that remain unclear. A new study dissects the role of METTL3-deposited global m 6 A RNA methylation in mediating this transcriptional dormancy.
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关键词
rna,pluripotency
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