Recent advances in the colorimetric and fluorescence analysis of bioactive small-molecule compounds based on the enzyme-like activity of nanomaterials
Journal of pharmaceutical and biomedical analysis(2023)
摘要
Nanomaterials with enzyme-like activity have been widely used in the construction of colorimetric and fluorescence sensors due to their advantages of cost-effectiveness, high stability, good biocompatibility, and ease of modification. Furthermore, the colorimetric and fluorescence sensors, which are effective approaches for detecting bioactive small-molecule compounds, have been extensively explored due to their simple operation and high sensitivity. Recent significant researches have focused on designing various sensors based on nanozymes with peroxidase- and oxidase-like activity for the colorimetric and fluorescence analysis of different analytes. In this review, recent developments (from 2018 to present) in the colorimetric and fluorescent analysis of bioactive small-molecule compounds based on the enzyme-like activity of nanomaterials were summarized. In addition, the challenges and design strategies in developing colorimetric and fluorescent assays with high performance and specific sensing were discussed.
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关键词
AA,AAO,ABTS,AChE,AR,ATP,AuNPs,BNPP,CAT,CDs,COF,CPP,Cys,DA,DMSNs,EDTA,GO,GOx,GSH,H2O2,hCAII,Hcy,HTA,La-MCM-41,LOD,MOF,MSU,NCs,NSs,TMB,OPD,OPH,OXD,oxTMB,PA,PDA,pNP,pNPA,POD,PorCOFs,ROS,RuO2,SD,SDM,SOD,ssDNA,ST,TA,UA,ZIF-8,ZIF-90,Bi2Fe4O9 NPs,BINOL
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