The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats.

Ting Cao,LiWei Wang,ShiMeng Jiao,Hui Chen, ChenQuan Lin,BiKui Zhang,HuaLin Cai

Neuropsychobiology（2023）

引用 0|浏览4

暂无评分

摘要

PGRMC1-overexpression could protect hippocampus-dependent cognitive impairment induced by clozapine. This effect appears to arise, in part, from the upregulated expression of PGRMC1/EGFR/GLP1R and the activation of downstream PI3K-Akt-BDNF and caspase-3 signaling pathways.

查看译文

关键词

pgrmc1 signaling,cognitive impairment induced,cognitive impairment,long-term

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要