Age and sex differences in the association between APOE genotype and Alzheimer's disease in a Taiwan Chinese population.

Ling-Chun Huang,Mei-Yueh Lee,Ching-Fang Chien,Yang-Pei Chang,Kuan-Ying Li,Yuan-Han Yang

Frontiers in aging neuroscience（2023）

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摘要

The ε4 allele represents a major risk factor for AD in the Taiwanese population. The effect of ε4 allele on AD risk appeared to be stronger among men aged 75 years or more and among younger women.

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关键词

Alzheimer's disease, apolipoprotein E gene, genetic association, sex and age stratified analyses, Taiwan Chinese population

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