Different oncological features of colorectal cancer codon-specific KRAS mutations: Not codon 13 but codon 12 have prognostic value.

Hong-Min Ahn,Duck-Woo Kim,Hyeon Jeong Oh,Hyung Kyung Kim,Hye Seung Lee, Tae Gyun Lee,Hye-Rim Shin,In Jun Yang,Jeehye Lee,Jung Wook Suh,Heung-Kwon Oh,Sung-Bum Kang

World journal of gastroenterology（2023）

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摘要

This study provides evidence that codon 13 mutation is less likely to serve as a prognostic biomarker than codon 12 mutation for CRC in a large-scale cohort.

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关键词

Genes, Ras, Codon, Colonic neoplasms, Rectal neoplasms

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