Validation and optimization of AFP-based biomarker panels for early HCC detection in Latin America and Europe.

Boris J B Beudeker,Siyu Fu,Domingo Balderramo,Angelo Z Mattos, Enrique Carrera,Javier Diaz,Jhon Prieto,Jesus Banales,Arndt Vogel,Marco Arrese,Jeffrey Oliveira,Zwier M A Groothuismink,Gertine van Oord,Bettina E Hansen,Robert A de Man,José D Debes,Andre Boonstra

Hepatology communications（2023）

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摘要

Our comprehensive analysis of large sample cohorts validates the GALAD score's utility in Latin American, Spanish, and Dutch patients for early-stage HCC detection. The optimized GALAD without AFP-L3, the ASAP score, is a good alternative and shows greater promise for HCC prediction.

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关键词

early hcc detection,biomarker panels,afp-based

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