Dendritic cell-based vaccine prepared with recombinant Lactococcus lactis enhances antigen cross-presentation and antitumor efficacy through ROS production.

Tingting Zhang,Xianxian Wei,Yijie Li,Shuai Huang, Yulin Wu,Shanshan Cai,Adila Aipire,Jinyao Li

Frontiers in immunology（2023）

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摘要

This study demonstrated that recombinant as an antigen delivery system prepared DC vaccine can enhance the antigen cross-presentation and antitumor efficacy.

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关键词

recombinant Lactococcus lactis, dendritic cell-based vaccine, reactive oxygen species, cross-presentation, antitumor efficacy

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