Long-term effectiveness of eculizumab: Data from the International PNH Registry.

Louis Terriou,Jong Wook Lee, Cecily Forsyth,Morag Griffin,Jeff Szer,Alexander Röth,Philippe Gustovic,Jesse Metzger,Ami S Patel,Christopher J Patriquin

European journal of haematology（2023）

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摘要

Using data from the largest Registry of patients with PNH, with ≥14 years of overall follow-up, we demonstrate that treatment with eculizumab conferred a 49% relative benefit in survival and an approximately 60% reduction in TE/MAVE risk.

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eculizumab,effectiveness

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