Programmed cell death protein 1 is a marker for neoadjuvant chemotherapy response in triple-negative breast cancer.

Maria de Fátima Dias Gaui, Luis Claudio Amendola, Danielle Carvalho Quintella,Nathalie Canedo, Adriana Bonomo

Revista da Associacao Medica Brasileira (1992)（2023）

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摘要

In this study, we observed that chemotherapy significantly increases stromal tumor-infiltrating lymphocytes, CD8 T cells, as well as CD8/FoxP3 ratio. Most importantly, programmed cell death protein 1 expression before neoadjuvant chemotherapy positively correlates with pathological response suggesting the use of programmed cell death protein 1 as a prognostic marker before neoadjuvant chemotherapy.

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关键词

cell death protein,neoadjuvant chemotherapy response,breast cancer,neoadjuvant chemotherapy,triple-negative

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