TAGAP expression influences CD4+ T cell differentiation, immune infiltration, and cytotoxicity in LUAD through the STAT pathway: implications for immunotherapy.

Zhanyu Xu,Tiaozhan Zheng,Zhiwen Zheng,Wei Jiang,Liuliu Huang,Kun Deng,Liqiang Yuan,Fanglu Qin,Yu Sun,Junqi Qin,Shikang Li

Frontiers in immunology（2023）

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摘要

TAGAP influences CD4+ T cell differentiation and function in LUAD through the STAT pathway, promoting immune infiltration and cytotoxicity. This study provides a scientific basis for developing novel LUAD immunotherapy strategies and exploring new therapeutic targets.

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关键词

immunotherapy,immune infiltration,luad,stat pathway,cytotoxicity

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