Modeling an ascending infection by Ureaplasma parvum and its cell signaling and inflammatory response at the feto-maternal interface.

Giovana Fernanda Cosi Bento,Lauren S Richardson,Márcia Guimarães da Silva,Ourlad Alzeus G Tantengco,Ramkumar Menon

American journal of reproductive immunology (New York, N.Y. : 1989)（2023）

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摘要

Our data suggest that U. parvum is poorly immunogenic and does not produce massive inflammatory changes at the feto-maternal interface. We speculate that the presence of U. parvum may still compromise the feto-maternal interface making it susceptible to other pathogenic infection.

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decidua, fetal membrane, infection, inflammation, organ-on-chip, pregnancy, preterm birth

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