When practice does not make a perfect - paradoxical learning curve in schizophrenia and bipolar disorder revealed by different serial reaction time task variants.

Adrian Andrzej Chrobak,Katarzyna Siuda-Krzywicka,Zbigniew Soltys, Sylwia Bielak, Dominik Nowaczek,Aleksandra Żyrkowska,Magdalena Fafrowicz,Tadeusz Marek, Ewa Pęcherzewska, Jan Kużdżał,Anna Starowicz-Filip,Aleksandra Gorostowicz,Dominika Dudek,Marcin Siwek

Frontiers in psychiatry（2023）

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摘要

The limited response time SRTT variant allowed us to replicate the findings of disrupted implicit motor learning in SZ and BD. The use of this paradigm in further neuroimaging studies may help to determine the neuronal underpinnings of this cognitive dysfunction in the abovementioned clinical groups.

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关键词

motor functions, movement disorders, cognition, cerebellum, procedural learning, affective disorders, sequence learning

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