Anti-SS-A Antibody is a Potential Predictor of Severe Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Retrospective Cohort Study.

To the Editor: Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) is a life-threatening mucocutaneous adverse reaction for which biomarkers are required to predict their severity and outcomes. In our clinical experience, patients with severe SJS/TEN frequently test positive for anti-SS-A antibody. This study aimed to investigate whether anti-SS-A positivity predicts disease severity and mortality in patients with SJS/TEN.