Results of a Multi-institutional Randomized Phase 3 Trial of Parotid-Sparing Whole Brain Radiotherapy.

K. Wang,C. Shen, H. D. Pacholke,A. Deal,K. A. Pearlstein,A. A. Weiner, V. Xu, F. Danquah,D. R. Wahl,W. C. Jackson,R. T. Dess,A. F. Dragovic,L. B. Marks,B. S. Chera,M. M. Kim

International journal of radiation oncology, biology, physics（2023）

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摘要

Parotid-sparing without coverage of the C1 vertebra appears safe and may meaningfully reduce acute xerostomia in patients with limited life expectancy who are candidates for conventional WBRT, although the study was underpowered to detect a significant difference at 1 month.

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