Predicting Acute Radio-Induced Toxicity for Head and Neck Cancer Patients: Combining Dosimetry with Biomarker Data, Disclosing a Synergistic Effect

S. Pereira,S. Deneuve,N. A. Iacovelli, M. Duclos, A. Cavallo,L. Nokovitch, P. E. Roux, D. Girodet, M. Poupart, P. Zrounba, L. Claude, L. Ferella,R. Valdagni,N. Foray,E. Orlandi, T. Rancati

International journal of radiation oncology, biology, physics（2023）

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摘要

These findings support the hypothesis that dose and biomarkers act synergistically; biologically based radiosensitivity plays a significant role when OARs are exposed at lower doses, while high doses of OARs determine toxicity irrespective of the underlying single pt biological characterization.

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关键词

neck cancer patients,neck cancer,dosimetry,radio-induced

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