Effect of cobalt-60 calibration dose-rate on arteriovenous malformation obliteration after stereotactic radiosurgery

Victoria Anthes, Michael Schwartz,Michael Cusimano,Ivan Radovanovic,Abhaya Kulkarni,Normand Laperriere,David Payne, Robert Heaton, Monique van Prooijen,Sunit Das,Derek Tsang

RADIOTHERAPY AND ONCOLOGY（2023）

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摘要

Patients with cerebral AVMs treated with higher SRS dose rates (from fresh cobalt-60 sources) experience higher incidences of obliteration, without a significant change in the risk of post-treatment edema. These findings suggest that clinics offering SRS for AVMs should regularly renew cobalt-60 radiation sources to maintain high therapeutic dose rates.

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关键词

arteriovenous malformation obliteration,stereotactic radiosurgery,dose-rate

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