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Surface modification of praseodymium oxide/hematite doped into Polycaprolactone for enhanced wound management demands

JOURNAL OF SAUDI CHEMICAL SOCIETY(2023)

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摘要
Praseodymium oxide (Pr6O11), hematite (Fe2O3), graphene oxide (GO), and polycaprolactone (PCL) based polymeric nanocomposites (NCs) are fabricated, aiming their usage as bioscaffold for medical purposes. Because of their distinctive light absorption and stability, Fe2O3 and Pr6O11 have been introduced as potential optical elements. The structure and size examination of NCs were executed by XRD, Raman, and FESEM. Pr6O11/Fe2O3/GO@PCL polymeric NC is exhibited Pr6O11, and Fe2O3 average size of 1.4, 0.4 mm, while average pores size 2.1 mm. As well, the Uv-Vis shows an absorption edge shifting along the x-axis that it begins with 3.1 eV for pure PCL, after that it declined to 1.7 eV for Pr6O11@PCL NC. Also, Pr6O11@PCL, and Pr6O11/ Fe2- O3@PCL NCs show the lowest similar contact angle with 38 & DEG;. Regarding cell attachment evaluation test, the Pr6O11/Fe2O3/GO@PCL NC healing valuation is touched -80%. As a result, the structure enabled 3-dimensional the division of normal cells, so promoting wound healing.& COPY; 2023 Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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关键词
Cell viability,Wound healing
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