Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas

Anne Hong-Hermesdorf,Marcus Miethke,Sean D Gallaher,Janette Kropat,Sheel C Dodani,Jefferson Chan,Dulmini Barupala,Dylan W Domaille, Dyna I Shirasaki,Joseph A Loo,Peter K Weber,Jennifer Pett-Ridge,Timothy L Stemmler,Christopher J Chang,Sabeeha S Merchant

NATURE CHEMICAL BIOLOGY（2014）

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摘要

collection of chemical tools and spectroscopic techniques demonstrate that Zn availability influences Cu + storage and localization in the green alga Chlamydomonas , with Zn limitation causing the accumulation of Cu + in lysosome-related organelles.

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nature chemical biology,science, science

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