A sensory signature of unaffected biological parents predicts the risk of autism in their offspring.

Chenyi Chen,Yawei Cheng,Chien-Te Wu,Chung-Hsin Chiang,Ching-Ching Wong,Chih-Mao Huang,Róger Marcelo Martínez,Ovid J L Tzeng,Yang-Teng Fan

Psychiatry and clinical neurosciences（2023）

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摘要

These findings provide support for hereditary basis of sensory alterations in ASD and suggest a potential avenue to improve ASD diagnosis by utilizing the sensory signature of biological parents, especially in families with a high risk of ASD. This approach holds promising prospects for early detection, even before the birth of the offspring. This article is protected by copyright. All rights reserved.

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关键词

autism spectrum disorder (ASD),endophenotype,machine learning,parent-child dyads,sensory responsivity

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