Foregoing elective neck dissection for elderly patients with oral cavity squamous cell carcinoma

Nir Tsur,Eyal Yosefof, Dean Dudkiewicz, Nofar Edri,Sagit Stern,Thomas Shpitzer,Aviram Mizrachi, Esmat Najjar

ANZ JOURNAL OF SURGERY(2024)

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摘要
Objective: Elective neck dissection (END) improves outcomes among clinically node-negative patients with oral cavity squamous cell carcinoma (OCSCC). However, END is of questionable value, considering the potentially higher comorbidities and operative risks in elderly patients.Methods: A retrospective review of all patients older than 65 years of age who were treated for OCSCC at a tertiary care centre between 2005 and 2020 was conducted.Results: Fifty-three patients underwent primary tumour resection alone, and 71 had simultaneous END. Most primary tumours were located on the mobile tongue. The patients who did not undergo END had a higher mean age (81.2 vs. 75.1 years, P < 0.00001), significantly shorter surgeries, and shorter hospitalizations. Occult cervical metastases were found in 24% of the patients who underwent END. The two groups showed no significant differences in overall survival or recurrence rates. Similar results were shown in a subpopulation analysis of patients older than 75 years.Conclusion: Foregoing END in elderly patients with no clinical evidence of neck metastases di: d not result in lower survival rates or higher recurrence rates.
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aged,carcinoma,elective neck dissection,humans,mouth neoplasms,old age,retrospective,squamous cell,squamous cell carcinoma of head and neck,survival rate
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