Implantable Cardioverter Defibrillator in Patients With Nonischemic Systolic Heart Failure With and Without Cardiac Resynchronization Therapy: Extended Follow-Up Study of the DANISH Trial

HomeCirculationVol. 148, No. 15Implantable Cardioverter Defibrillator in Patients With Nonischemic Systolic Heart Failure With and Without Cardiac Resynchronization Therapy: Extended Follow-Up Study of the DANISH Trial No AccessResearch ArticleRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessResearch ArticleRequest AccessFull TextImplantable Cardioverter Defibrillator in Patients With Nonischemic Systolic Heart Failure With and Without Cardiac Resynchronization Therapy: Extended Follow-Up Study of the DANISH Trial Jawad H. Butt, Adelina Yafasova, Seiko N. Doi, Jens C. Nielsen, Jens Haarbo, Hans Eiskjær, Axel Brandes, Anna M. Thøgersen, Finn Gustafsson, Christian Hassager, Jesper H. Svendsen, Dan E. Høfsten, Lars Videbæk, Christian Torp-Pedersen, Steen Pehrson, Jens Jakob Thune and Lars Køber Jawad H. ButtJawad H. Butt Correspondence to: Jawad H. Butt, MD, Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark. Email E-mail Address: [email protected] https://orcid.org/0000-0002-7380-4144 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Search for more papers by this author , Adelina YafasovaAdelina Yafasova https://orcid.org/0000-0003-3889-0080 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Search for more papers by this author , Seiko N. DoiSeiko N. Doi Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Search for more papers by this author , Jens C. NielsenJens C. Nielsen https://orcid.org/0000-0001-9414-1653 Department of Cardiology, Aarhus University Hospital, Denmark (J.C.N., H.E.). Department of Clinical Medicine, Aarhus University, Denmark (J.C.N.). Search for more papers by this author , Jens HaarboJens Haarbo Department of Cardiology, Copenhagen University Hospital–Herlev and Gentofte, Hellerup, Denmark (J.H., L.K.). Search for more papers by this author , Hans EiskjærHans Eiskjær https://orcid.org/0000-0003-1520-1924 Department of Cardiology, Aarhus University Hospital, Denmark (J.C.N., H.E.). Search for more papers by this author , Axel BrandesAxel Brandes https://orcid.org/0000-0001-9145-6887 Department of Cardiology, Odense University Hospital, Denmark (A.B.). Department of Clinical Research, University of Southern Denmark, Odense (A.B.). Department of Cardiology, University Hospital of Southern Denmark, Esbjerg (A.B.). Search for more papers by this author , Anna M. ThøgersenAnna M. Thøgersen Department of Cardiology, Aalborg University Hospital, Denmark (A.M.T.). Search for more papers by this author , Finn GustafssonFinn Gustafsson https://orcid.org/0000-0003-2144-341X Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Department of Clinical Medicine, University of Copenhagen, Denmark (F.G., C.H., J.H.S., D.E.H., J.J.T.). Search for more papers by this author , Christian HassagerChristian Hassager https://orcid.org/0000-0002-1199-0981 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Department of Clinical Medicine, University of Copenhagen, Denmark (F.G., C.H., J.H.S., D.E.H., J.J.T.). Search for more papers by this author , Jesper H. SvendsenJesper H. Svendsen https://orcid.org/0000-0001-8466-8515 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Department of Clinical Medicine, University of Copenhagen, Denmark (F.G., C.H., J.H.S., D.E.H., J.J.T.). Search for more papers by this author , Dan E. HøfstenDan E. Høfsten https://orcid.org/0000-0002-7609-4141 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Department of Clinical Medicine, University of Copenhagen, Denmark (F.G., C.H., J.H.S., D.E.H., J.J.T.). Search for more papers by this author , Lars VidebækLars Videbæk https://orcid.org/0000-0001-7740-1564 Department of Cardiology, Odense University Hospital, Svendborg, Denmark (L.V.). Search for more papers by this author , Christian Torp-PedersenChristian Torp-Pedersen https://orcid.org/0000-0003-2892-6131 Department of Cardiology, Nordsjællands Hospital, Hillerød, Denmark (C.T.-P.). Department of Public Health, University of Copenhagen, Denmark (C.T.-P.). Search for more papers by this author , Steen PehrsonSteen Pehrson https://orcid.org/0000-0002-7149-4613 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Search for more papers by this author , Jens Jakob ThuneJens Jakob Thune https://orcid.org/0000-0002-3621-3775 Department of Clinical Medicine, University of Copenhagen, Denmark (F.G., C.H., J.H.S., D.E.H., J.J.T.). Department of Cardiology, Copenhagen University Hospital–Bispebjerg and Frederiksberg, Copenhagen, Denmark (J.J.T.). Search for more papers by this author and Lars KøberLars Køber https://orcid.org/0000-0002-6635-1466 Department of Cardiology, Copenhagen University Hospital–Rigshospitalet, Denmark (J.W.B., A.Y., S.N.D., F.G., C.H., J.H.S., D.E.H., S.P., L.K.). Department of Cardiology, Copenhagen University Hospital–Herlev and Gentofte, Hellerup, Denmark (J.H., L.K.). Search for more papers by this author Originally published9 Oct 2023https://doi.org/10.1161/CIRCULATIONAHA.123.065560Circulation. 2023;148:1179–1181FootnotesRegistration: URL, https://www.clinicaltrials.gov; Unique identifier: NCT00542945.Circulation is available at www.ahajournals.org/journal/circFor Sources of Funding and Disclosures, see page 1181.Correspondence to: Jawad H. Butt, MD, Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark. Email jawad_butt91@hotmail.comREFERENCES1. Heidenreich PA, Bozkurt B, Aguilar D, Allen LA, Byun JJ, Colvin MM, Deswal A, Drazner MH, Dunlay SM, Evers LR, et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.Circulation. 2022; 145:e895–e1032. doi: 10.1161/CIR.0000000000001063LinkGoogle Scholar2. Shen L, Jhund PS, Petrie MC, Claggett BL, Barlera S, Cleland JGF, Dargie HJ, Granger CB, Kjekshus J, Køber L, et al. Declining risk of sudden death in heart failure.N Engl J Med. 2017; 377:41–51. doi: 10.1056/NEJMoa1609758CrossrefMedlineGoogle Scholar3. Køber L, Thune JJ, Nielsen JC, Haarbo J, Videbæk L, Korup E, Jensen G, Hildebrandt P, Steffensen FH, Bruun NE, et al; DANISH Investigators. Defibrillator implantation in patients with nonischemic systolic heart failure.N Engl J Med. 2016; 375:1221–1230. doi: 10.1056/NEJMoa1608029CrossrefMedlineGoogle Scholar4. Doran B, Mei C, Varosy PD, Kao DP, Saxon LA, Feldman AM, DeMets D, Bristow MR. The addition of a defibrillator to resynchronization therapy decreases mortality in patients with nonischemic cardiomyopathy.JACC Heart Fail. 2021; 9:439–449. doi: 10.1016/j.jchf.2021.02.013CrossrefMedlineGoogle Scholar5. ClinicalTrials.gov. Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure.Accessed August 1, 2023. https://clinicaltrials.gov/ct2/show/NCT03494933Google Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails October 10, 2023Vol 148, Issue 15 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.123.065560PMID: 37812653 Originally publishedOctober 9, 2023 Keywordscardiac resynchronization therapyimplantable cardioverter defibrillatordeath, sudden, cardiacheart failureclinical trialmortalityPDF download Advertisement SubjectsHeart Failure