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Application of Multigene Panel Detection in Breast Cancer

Yuan Zhao,Dun Xiong, Bo Yang,Shaocai Xia, Xinzhi Zhang

JPMA The Journal of the Pakistan Medical Association(2023)

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摘要
Precision medicine will be the direction of future medical development, especially in cancer diagnosis and treatment. With the deepening of breast cancer-related research, new factors related to diagnosis, treatment and prognosis are constantly being discovered. Researchers combine different factorsto form a multigene panel testing, guiding clinicians' decision-making. The application scope of multigene panel detection is constantly expanding. At present, it has been tried in the prognosis evaluation of lymph node-positive and human epidermal growth factor receptor 2-positive breast cancer patients and the early screening of breast cancer. With continuous technological advancement, there will be broader application prospects in the future. The current narrative review was planned to evaluate the recent advances in applying multigene panel testing in breast cancer cases.
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关键词
Multigene panel testing, Breast cancer,Oncotype Dx, MammaPrint, Endopredict, PAM50, BCI,CancerSeek.
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