L-glutathione 1% promotes neuroprotection of nitrergic neurons and reduces the oxidative stress in the jejunum of rats with Walker-256-bearing tumor.

Ana Paula de Oliveira,Juliana Vanessa Colombo Martins Perles,Sara Raquel Garcia de Souza, Sabrina Silva Sestak,Fabiana Galvão da Motta Lima, Gustavo Henrique Doná Rodrigues Almeida, Lídia Rodrigues Cicero,Naianne Kelly Clebis,Flávia Alessandra Guarnier, Fernanda Pascoal Blegniski,Roseane Carvalho Vasconcelos,Aurigena Antunes Araújo,Jurandir Fernando Comar,Lucas Stafuza Moreira,Camila Cavicchioli Sehaber-Sierakowski,Kassio Papi Silva Zanoni,Jacqueline Nelisis Zanoni

Neurogastroenterology and motility（2023）

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摘要

The treatment with L-glutathione (1%) imposed an important defense to some parameters of oxidative stress induced by TW-256, leading to neuroprotection to the loss in the nNOS-IR neuron density.

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关键词

antioxidant, cancer, cytokines, enteric nervous system, neoplasia, reactive species

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